Papers

• Kanayama, M. et al. Enhanced capture system for mesenchymal‑type circulating tumor cells using a polymeric microfluidic device 'CTC‑Chip' incorporating cell‑surface vimentin. Oncol Rep. 52, 156 (2024)
• Kase, A. et al. Effect of micropost geometry on capture of circulating tumor cells. Journal of Biorheology 37(2), 112-119 (2023)
• Kanayama, M. et al. Prognostic impact of circulating tumor cells detected with the microfluidic "universal CTC-chip" for primary lung cancer. Cancer Sci. 113, 1028-1037 (2022)
• Takashi Ohnaga, Enabling custom-made cancer treatment. Development of a system to capture and analyze circulating cancer cells in the blood, Hokuriku Economic Research, July 2022, 30-31 (2022)
• Kanayama, M. et al. Novel circulating tumor cell‑detection chip combining conventional podoplanin and EGFR antibodies for all histological malignant pleural mesothelioma Oncol Lett. 22, 522 (2021)
• Kure, K. et al. Using the polymeric circulating tumor cell chip to capture circulating tumor cells in blood samples of patients with colorectal cancer. Oncol Lett. 19, 2286-2294 (2020)
• Obayashi, K. et al. Initial detection of circulating tumor cells from metastatic prostate cancer patients with a novel small device. Prostate International 7, 131-138 (2019)
• Ishibashi, R. et al. Detection of circulating colorectal cancer cells by a custom microfluid system before and after endoscopic metallic stent placement. Oncol Lett. 18, 6397-6404 (2019)
• Yoneda, K. et al. Detection of circulating tumor cells with a novel microfluidic system in malignant pleural mesothelioma. Cancer Sci. 110, 726-733 (2019)
• Ohnaga, T. et al. Highly efficient capture of cancer cells expressing EGFR by microfluidic methods based on antigen-antibody association. Sci Rep. 8, 12005 (2018)
• Yoneda, K. et al. Capture of mesothelioma cells with 'universal' CTC-chip. Oncol Lett. 15, 2635-2640 (2018)
• Takashi Ohnaga et al. Liquid biopsy - Detection and analysis technology of tumor markers in body fluids - CMC Publishing, 288 (2017)
• Chikaishi, Y. et al. EpCAM-independent capture of circulating tumor cells with a 'universal CTC-chip'. Oncol Rep. 37, 77-82 (2017)
• Ohnaga, T. et al. Capture of esophageal and breast cancer cells with polymeric microfluidic devices for CTC isolation. Mol Clin Oncol. 4, 599-602 (2016)
• Takuya Nagata et al. Identification of CTCs in peripheral blood of breast cancer patients and prediction of anticancer drug sensitivity using a new blood-floating cancer cell (CTC) capture system. Cancer and Chemotherapy, Vol. 42, 1240 (2015)
• Ohnaga, T. et al. Polymeric microfluidic devices exhibiting sufficient capture of cancer cell line for isolation of circulating tumor cells. Biomed Microdevices 15, 611-616 (2013)

Patents

• JP5802894B2 Microfluidic chip
• JP5799395B2 Microchip that can capture suspended cancer cells in blood
• JP5326089B2 Functional fine structure
• JP4714805B2 Microchip
• JP4418880B2 Microstructure with micro structure on the surface